At the beginning of the pandemic, Mel and a group of ladies are determined to tackle the critical social issues of the day. Tania must accept abrupt uncertainty and allow herself to wrestle with the viral infection thrown in her direction. Citizens take to the streets in protest of the current social and racial injustices facing the nation. Meanwhile, in a rural hideout, a militia group plots a revolt against state and national leadership, unable to come to terms with a rapidly changing society. As the virus takes its global toll, a retired Mr. B takes the news in stride, while germaphobe Luanne flees the city in an attempt to protect her sanity and young family from the stark realities of the time.