Colgate Sensitive Pro-Relief sensitivity toothpaste is clinically proven for instant and lasting† relief from sensitivity pain. With regular use, the Pro-Argin formula builds a long-lasting protective barrier that acts like a seal against sensitivity. With regular brushing, Colgate Sensitive Pro-Relief Complete Protection sensitivity toothpaste helps to strengthen enamel, promote gum health, fight cavities and remove plaque and surface stains. Plus it has the freshness you trust from Colgate. †For instant relief, apply directly to the sensitive tooth with fingertip and gently massage for 1 minute. Brush twice daily and use regularly for lasting sensitivity relief and cavity protection.