The type of cancer that involves an abnormal growth of skin cells is called skin cancer. There are three prominent forms of this type of cancer named as basal cell carcinoma, squamous cell carcinoma, and melanoma. The main reason for development of skin cancer is exposure of skin to sun, and usually includes lips, ears, neck, face, and scalp. Basal cell carcinoma may appear like a pearly or waxy bump or as a flat, flesh colored scar-like lesion. Squamous cell carcinoma often affects people with darker skin tone and appears as a firm red nodule or as a flat lesion with a scaly crusted surface. The signs of melanoma include a large brownish spot with darker speckles, a painful lesion that itches or burns, or as a mole that changes in color and size. A weakened immune system, exposure to radiation, a personal history of skin cancer, fair skin, and excessive sun exposure are some factors that increase the risk of skin cancer. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the prevention and treatment of skin cancer. It aims to shed light on some of the unexplored aspects of this disease. The book will serve as a reference to a broad spectrum of readers.